Article
Combining the case-control methodology with the small size transmission/disequilibrium test for multiallelic markers.
European journal of human genetics : EJHG - 1 Sept 2005
Guo Wei, Fung Wing K
Abstract excerpt
Case-control studies compare marker-allele distributions in affected and unaffected individuals, and significant results may be due to linkage but can also simply reflect population structure. To test for linkage after obtaining a significant case-control finding, within-family analysis can be performed. In a transmission/disequilibrium test (TDT), genotypes of cases are compared to those of their parents to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
