Article
TDT statistics for mapping quantitative trait loci.
Annals of human genetics - 1 Sept 1998
Xiong M M, Krushkal J, Boerwinkle E
Abstract excerpt
The original transmission disequilibrium test (TDT), was introduced to test for linkage between a marker and a disease-susceptibility locus (Spielman et al. 1993). Allison (1997) extended the TDT procedure to quantitative traits. Allison's test, however, is restrictive in that it requires family trios consisting of one heterozygous parent, one homozygous parent and one child, and considers only the situation...
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