Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Power studies for the transmission/disequilibrium tests with multiple alleles.

American journal of human genetics - 1 Mar 1997

Kaplan N L, Martin E R, Weir B S

Abstract excerpt

Case-control studies compare marker-allele distributions in affected and unaffected individuals, and significant results suggest linkage but may simply reflect population structure. For markers with m alleles (m > or = 2), a McNemar-like statistic, I, estimates the level of population association between marker and disease loci. To test for linkage after significant case-control tests, within-family tests are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Genetic Markers
Share to Genetic Techniques

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Models, Genetic

Share to Models, Statistical

Share to Monte Carlo Method

Source

Open in PubMed Open full text

Identifiers

PMID: 9042930
PMCID: PMC1712498

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Power studies for the transmission/disequilibrium tests with multiple alleles.PMID 9042930Read ↗

Combining the case-control methodology with the small size transmission/disequilibrium test for multiallelic markers.Semantic proximity Read ↗

Transmission disequilibrium test with discordant sib pairs when parents are available.Semantic proximity Read ↗

Method for using complete and incomplete trios to identify genes related to a quantitative trait.Semantic proximity Read ↗

Relationship between case-control studies and the transmission/disequilibrium test.Semantic proximity Read ↗

An evaluation of power and type I error of single-nucleotide polymorphism transmission/disequilibrium-based statistical methods under different family structures, missing parental data, and population stratification.Semantic proximity Read ↗

Tests for linkage and association in nuclear families.Semantic proximity Read ↗

Analytic power and sample size calculation for the genotypic transmission/disequilibrium test in case-parent trio studies.Semantic proximity Read ↗

Catmap: case-control and TDT meta-analysis package.Semantic proximity Read ↗

Inferring haplotype/disease association by joint use of case-parents trios and case-parent pairs.Semantic proximity Read ↗

The power of the transmission disequilibrium test (TDT) with both case-parent and control-parent trios.Semantic proximity Read ↗

The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits.Semantic proximity Read ↗

Power analysis of C-TDT for small sample size genome-wide association studies by the joint use of case-parent trios and pairs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.