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Article

Removing phenotypic distribution assumptions from tests of linkage disequilibrium for quantitative traits.

Genetic epidemiology - 1 Apr 2003

Alcaïs Alexandre, Abel Laurent

Abstract excerpt

The transmission disequilibrium test (TDT) has become a family-based method of reference to search for linkage disequilibrium (LD). Although it was first developed for dichotomous traits, numerous approaches have extended the TDT to quantitative phenotypes that either rely on regression or variance component techniques. Both of these approaches are based on some phenotypic distribution assumptions, the violation...

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PMID: 12652523
DOI: 10.1002/gepi.10220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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