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Article

Cytoplasmic dynein intermediate chain phosphorylation regulates binding to dynactin.

The Journal of biological chemistry - 13 Jul 2001

Vaughan P S, Leszyk J D, Vaughan K T

Abstract excerpt

Previously, we identified dynactin as a cargo receptor or adaptor for cytoplasmic dynein, mediated by an interaction between the dynein intermediate chain and p150(Glued). To test phosphorylation as a potential regulatory mechanism for this interaction, we analyzed cytoplasmic dynein by two-dimensional gel analysis and detected two intermediate chain variants, one of which was eliminated by phosphatase treatment....

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Identifiers

PMID: 11340075
DOI: 10.1074/jbc.M102649200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cytoplasmic dynein intermediate chain phosphorylation regulates binding to dynactin.PMID 11340075Read ↗

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