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Article

Dynein light intermediate chain: an essential subunit that contributes to spindle checkpoint inactivation.

Molecular biology of the cell - 1 Nov 2008

Mische Sarah, He Yungui, Ma Lingzhi, Li Mingang, Serr Madeline, Hays Thomas S

Abstract excerpt

The dynein light intermediate chain (LIC) is a subunit unique to the cytoplasmic form of dynein, but how it contributes to dynein function is not fully understood. Previous work has established that the LIC homodimer binds directly to the dynein heavy chain and may mediate the attachment of dynein to centrosomes and other cargoes. Here, we report our characterization of the LIC in Drosophila. Unlike vertebrates,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18799620
DOI: 10.1091/mbc.e08-05-0483
PMCID: PMC2575169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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