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Article

Phosphorylation controls autoinhibition of cytoplasmic linker protein-170.

Molecular biology of the cell - 1 Aug 2010

Lee Ho-Sup, Komarova Yulia A, Nadezhdina Elena S, Anjum Rana, Peloquin John G, Schober Joseph M, Danciu Oana, van Haren Jeffrey, Galjart Niels, Gygi Steven P, Akhmanova Anna, Borisy Gary G

Abstract excerpt

Cytoplasmic linker protein (CLIP)-170 is a microtubule (MT) plus-end-tracking protein that regulates MT dynamics and links MT plus ends to different intracellular structures. We have shown previously that intramolecular association between the N and C termini results in autoinhibition of CLIP-170, thus altering its binding to MTs and the dynactin subunit p150(Glued) (J. Cell Biol. 2004: 166, 1003-1014). In this...

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Identifiers

PMID: 20519438
DOI: 10.1091/mbc.e09-12-1036
PMCID: PMC2912352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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