Article
Dynactin-membrane interaction is regulated by the C-terminal domains of p150(Glued).
EMBO reports - 1 Oct 2001
Kumar S, Zhou Y, Plamann M
Abstract excerpt
Dynactin has been proposed to link the microtubule-associated motor cytoplasmic dynein with membranous cargo; however, the mechanism by which dynactin-membrane interaction is regulated is unknown. Here we show that dynein and dynactin exist in discrete cytosolic and membrane-bound states in the filamentous fungus Neurospora crassa. Results from in vitro membrane-binding studies show that dynein and...
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