Article
Regulation of cytoplasmic dynein function in vivo by the Drosophila Glued complex.
The Journal of cell biology - 1 Oct 1995
McGrail M, Gepner J, Silvanovich A, Ludmann S, Serr M, Hays T S
Abstract excerpt
The Drosophila Glued gene product shares sequence homology with the p150 component of vertebrate dynactin. Dynactin is a multiprotein complex that stimulates cytoplasmic dynein-mediated vesicle motility in vitro. In this report, we present biochemical, cytological, and genetic evidence that demon...
Topics
- Animals
- Drosophila
- Dynactin Complex
- Dyneins
- Female
- Gene Expression
- Microtubule Proteins
- Microtubule-Associated Proteins
- Microtubules
- Mutation
- Oogenesis