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Article

Genetic dissection of nodal function in patterning the mouse embryo.

Development (Cambridge, England) - 1 May 2001

Lowe L A, Yamada S, Kuehn M R

Abstract excerpt

Loss-of-function analysis has shown that the transforming growth factor-like signaling molecule nodal is essential for mouse mesoderm development. However, definitive proof of nodal function in other developmental processes in the mouse embryo has been lacking because the null mutation blocks gastrulation. We describe the generation and analysis of a hypomorphic nodal allele. Mouse embryos heterozygous for the...

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Identifiers

PMID: 11311163
DOI: 10.1242/dev.128.10.1831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic dissection of nodal function in patterning the mouse embryo.PMID 11311163Read ↗

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