Article
Relationship between asymmetric nodal expression and the direction of embryonic turning.
Nature - 9 May 1996
Collignon J, Varlet I, Robertson E J
Abstract excerpt
Growth factors related to TGF-beta provide important signals for patterning the vertebrate body plan. One such family member, nodal, is required for formation of the primitive streak during mouse gastrulation. Here we have used a nodal-lacZ reporter allele to demonstrate asymmetric nodal expressi...
Topics
- Animals
- Base Sequence
- DNA Primers
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Female
- Gastrula
- Gene Expression Regulation, Developmental
- Hedgehog Proteins
- Hepatocyte Nuclear Factor 3-beta
- Lac Operon
- Male
- Mesoderm
- Mice
- Molecular Sequence Data
- Mutagenesis, Insertional
- Mutation
- Nodal Protein
