Article
Relationship between asymmetric nodal expression and the direction of embryonic turning.
Nature - 9 May 1996
Collignon J, Varlet I, Robertson E J
Abstract excerpt
Growth factors related to TGF-beta provide important signals for patterning the vertebrate body plan. One such family member, nodal, is required for formation of the primitive streak during mouse gastrulation. Here we have used a nodal-lacZ reporter allele to demonstrate asymmetric nodal expression in the mouse node, a structure thought to be the functional equivalent of the frog and chick 'organizer', and in...
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