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Article

Cell fate decisions within the mouse organizer are governed by graded Nodal signals.

Genes & development - 1 Jul 2003

Vincent Stephane D, Dunn N Ray, Hayashi Shigemi, Norris Dominic P, Robertson Elizabeth J

Abstract excerpt

It is well known that cell fate decisions in the mouse organizer region during gastrulation ultimately govern gut formation and patterning, left-right axis determination, and development of the central nervous system. Previous studies suggest that signaling pathways activated by Nodal, bone morphogenetic protein (BMP), and Wnt ligands coordinately regulate patterning of the streak and the formation of midline...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12842913
DOI: 10.1101/gad.1100503
PMCID: PMC196136

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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