Article
Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation.
Nature - 11 Feb 1993
Zhou X, Sasaki H, Lowe L, Hogan B L, Kuehn M R
Abstract excerpt
During gastrulation, the three germ layers of the embryo are formed and organized along the anterior-posterior body axis. In the mouse, gastrulation involves the delamination of ectodermal cells through the primitive streak and their differentiation into mesoderm. These processes do not occur in embryos homozygous for a retrovirally induced recessive prenatal lethal mutation, the strain 413-d insertional...
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