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Article

Nodal Expression in the Uterus of the Mouse Is Regulated by the Embryo and Correlates with Implantation1

27 Jan 2011

Abstract excerpt

Nodal, a transforming growth factor beta (TGFB) superfamily member, plays a critical role during early embryonic development. Recently, components of the Nodal signaling pathway were characterized in the human uterus and implicated in the tissue remodeling events during menstruation. Furthermore, the Nodal inhibitor, Lefty, was identified in the mouse endometrium during pregnancy, and its overexpression led to...

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PMID: 21270430
DOI: 10.1095/biolreprod.110.087239

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Nodal Expression in the Uterus of the Mouse Is Regulated by the Embryo and Correlates with Implantation1PMID 21270430Read ↗

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Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation.Semantic proximity Read ↗

Nodal and bone morphogenetic protein 5 interact in murine mesoderm formation and implantation.Semantic proximity Read ↗

Integrated chromatin immunoprecipitation sequencing and microarray analysis identifies FOXA2 target genes in the glands of the mouse uterusSemantic proximity Read ↗

Complex expression patterns support potential roles for maternally derived activins in the establishment of pregnancy in mouseSemantic proximity Read ↗

Homeobox genes for embryo implantation: From mouse to humanSemantic proximity Read ↗

LEFTY2 inhibits endometrial receptivity by downregulating Orai1 expression and store-operated Ca2+ entrySemantic proximity Read ↗

Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract.Semantic proximity Read ↗

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