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Article

Apoptosis induced by Rac GTPase correlates with induction of FasL and ceramides production.

Molecular biology of the cell - 1 Dec 2000

Embade N, Valerón P F, Aznar S, López-Collazo E, Lacal J C

Abstract excerpt

Rho proteins, members of the Ras superfamily of GTPases, are critical elements in signal transduction pathways governing cell proliferation and cell death. Different members of the family of human Rho GTPases, including RhoA, RhoC, and Rac1, participate in the regulation of apoptosis in response to cytokines and serum deprivation in different cell systems. Here, we have characterized the mechanism of apoptosis...

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Identifiers

PMID: 11102528
DOI: 10.1091/mbc.11.12.4347
PMCID: PMC15077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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