Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A caspase-8-independent component in TRAIL/Apo-2L-induced cell death in human rhabdomyosarcoma cells.

Cell death and differentiation - 1 Jun 2003

Petak I, Vernes R, Szucs K S, Anozie M, Izeradjene K, Douglas L, Tillman D M, Phillips D C, Houghton J A

Abstract excerpt

Tumor necrosis factor related apoptosis inducing ligand (TRAIL) belongs to the Tumor necrosis factor (TNF) family of death-inducing ligands, and signaling downstream of TRAIL ligation to its receptor(s) remains to be fully elucidated. Components of the death-inducing signaling complex (DISC) and TRAIL signaling downstream of receptor activation were examined in TRAIL - sensitive and -resistant models of human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to bcl-X Protein
Share to BH3 Interacting Domain Death Agonist Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caspase 8

Share to Fas-Associated Death Domain Protein

Share to Rhabdomyosarcoma

Share to Sphingomyelins

Share to Sphingosine

Share to TNF-Related Apoptosis-Inducing Ligand

Source

Identifiers

PMID: 12761581
DOI: 10.1038/sj.cdd.4401232

Genes

FADD
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A caspase-8-independent component in TRAIL/Apo-2L-induced cell death in human rhabdomyosarcoma cells.PMID 12761581Read ↗

Caspase-8 regulation of TRAIL-mediated cell death.Semantic proximity Read ↗

The TRAIL apoptotic pathway in cancer onset, progression and therapy.Semantic proximity Read ↗

Therapeutic applications of TRAIL receptor agonists in cancer and beyondSemantic proximity Read ↗

Mechanisms of resistance to TRAIL-induced apoptosis in cancer.Semantic proximity Read ↗

[TNF-related apoptosis-inducing ligand signaling pathway and hematopoietic malignancies].Semantic proximity Read ↗

Autophagy modulates temozolomide-induced cell death in alveolar Rhabdomyosarcoma cellsSemantic proximity Read ↗

TRAIL as a target in anti-cancer therapy.Semantic proximity Read ↗

TRAIL triggers apoptosis in human malignant glioma cells through extrinsic and intrinsic pathways.Semantic proximity Read ↗

TRAIL/Apo-2-ligand-induced apoptosis in human T cellsSemantic proximity Read ↗

Bid Mediates Apoptotic Synergy between Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) and DNA DamageSemantic proximity Read ↗

Transforming growth factor-beta-mediated tumor necrosis factor-related apoptosis-inducing ligand expression and apoptosis in hepatoma cells requires functional cooperation between Smad proteins and activator protein-1.Semantic proximity Read ↗

Conversion of Bcl-2 to a Bax-like death effector by caspases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.