Apoptosis regulated by a death factor and its receptor: Fas ligand and Fas.

doi:10.1098/rstb.1994.0107

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Article

Apoptosis regulated by a death factor and its receptor: Fas ligand and Fas.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 30 Aug 1994

Nagata S

Abstract excerpt

Homeostasis in vertebrates is tightly regulated by not only proliferation and differentiation of cells, but also cell death or apoptosis (Ellis et al. 1991; Raff 1992). Many cytokines bind to their respective receptors to regulate proliferation and differentiation of cells. Our recent studies on...

Topics

Animals
Antigens, Surface
Apoptosis
Cytotoxicity, Immunologic
Humans
Mutation
T-Lymphocytes, Cytotoxic
fas Receptor

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