Article
Engulfment of apoptotic cells is negatively regulated by Rho-mediated signaling.
The Journal of biological chemistry - 12 Dec 2003
Tosello-Trampont Annie-Carole, Nakada-Tsukui Kumiko, Ravichandran Kodi S
Abstract excerpt
The rapid and efficient phagocytosis of apoptotic cells plays a critical role in preventing secondary necrosis, inflammation as well as in tissue remodeling and regulating immune responses. However, the molecular details of engulfment are just beginning to be elucidated. Among the Rho family GTPa...
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