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Article

Localization of a small genomic region associated with elevated ACE.

American journal of human genetics - 1 Nov 2000

Zhu X, McKenzie C A, Forrester T, Nickerson D A, Broeckel U, Schunkert H, Doering A, Jacob H J, Cooper R S, Rieder M J

Abstract excerpt

Defining the relationship between multiple polymorphisms in a small genomic region and an underlying quantitative trait locus (QTL) represents a major challenge in human genetics. Pedigree analyses have shown that angiotensin I-converting enzyme (ACE) levels are influenced by a QTL located within or close to the ACE gene and most likely resides in the 3' region of this locus. We genotyped seven polymorphisms...

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Identifiers

PMID: 11001581
DOI: 10.1016/S0002-9297(07)62945-0
PMCID: PMC1288557

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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