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Article

Angiotensin-1-converting enzyme (ACE) plasma concentration is influenced by multiple ACE-linked quantitative trait nucleotides.

Human molecular genetics - 1 Nov 2002

Cox Roger, Bouzekri Nourdine, Martin Sabrina, Southam Lorraine, Hugill Alison, Golamaully Mahamadee, Cooper Richard, Adeyemo Adebowale, Soubrier Florent, Ward Ryk, Lathrop G Mark, Matsuda Fumihiko, Farrall Martin

Abstract excerpt

Circulating angiotensin-1-converting enzyme (ACE) is a highly heritable trait, and a major component of the genetic variance maps to the region of the ACE gene. The strong effect of the locus, and the interest in ACE as a candidate gene for cardiovascular disorders, has led to extensive investigation of its relationship to the ACE phenotype, providing one of the most complete examples of quantitative trait locus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12393808
DOI: 10.1093/hmg/11.23.2969

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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