Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis.

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Article

Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis.

American journal of human genetics - 1 Jun 1996

Villard E, Tiret L, Visvikis S, Rakotovao R, Cambien F, Soubrier F

Abstract excerpt

Plasma angiotensin I-converting enzyme (ACE) levels are highly genetically determined. A previous segregation-linkage analysis suggested the existence of a functional mutation located within or close to the ACE locus, in almost complete linkage desequilibrium (LD) with the ACE insertion/deletion...

Topics

Adolescent
Adult
Alleles
Base Sequence
DNA Primers
DNA Transposable Elements
Female
Genetic Linkage
Genotype
Haplotypes
Homozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Linkage Disequilibrium

Male

Molecular Sequence Data

Nuclear Family

Oligopeptides

Peptidyl-Dipeptidase A

Source

Open in PubMed Open full text

Identifiers

PMID: 8651305
PMCID: PMC1915072

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8651305-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis.PMID 8651305Read ↗

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