Measured haplotype analysis of the angiotensin-I converting enzyme gene.

doi:10.1093/hmg/7.11.1745

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Article

Measured haplotype analysis of the angiotensin-I converting enzyme gene.

Human molecular genetics - 1 Oct 1998

Keavney B, McKenzie C A, Connell J M, Julier C, Ratcliffe P J, Sobel E, Lathrop M, Farrall M

Abstract excerpt

Linkage and segregation analysis have shown that circulating angiotensin-I converting enzyme (ACE) levels are influenced by a major quantitative trait locus that maps within or close to the ACE gene. The D variant of a 287 bp insertion/deletion (I/D) polymorphism in intron 16 of the gene is assoc...

Topics

England
Evolution, Molecular
Genetic Techniques
Genetic Variation
Haplotypes
Humans
Peptidyl-Dipeptidase A
Polymorphism, Genetic
Quantitative Trait, Heritable
White People

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