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Article

Application of a two-phenotype color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment.

Mathematical biosciences - 1 Apr 2010

Groos Jutta, Kopp-Schneider Annette

Abstract excerpt

The color-shift model (CSM) was introduced by Kopp-Schneider et al. [1] to describe formation and progression of foci of altered hepatocytes (FAH). It incorporates the field-effect hypothesis which postulates that entire colonies of altered hepatocytes simultaneously alter their phenotype. In the original CSM, FAH grow with deterministic growth rate and change their phenotype after an exponentially distributed...

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Source

Identifiers

PMID: 20043929
DOI: 10.1016/j.mbs.2009.12.009

Genes

FAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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