Article
Application of a two-phenotype color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment.
Mathematical biosciences - 1 Apr 2010
Groos Jutta, Kopp-Schneider Annette
Abstract excerpt
The color-shift model (CSM) was introduced by Kopp-Schneider et al. [1] to describe formation and progression of foci of altered hepatocytes (FAH). It incorporates the field-effect hypothesis which postulates that entire colonies of altered hepatocytes simultaneously alter their phenotype. In the...
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