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Article

The protofilament substructure of amyloid fibrils.

Journal of molecular biology - 28 Jul 2000

Serpell L C, Sunde M, Benson M D, Tennent G A, Pepys M B, Fraser P E

Abstract excerpt

Tissue deposition of normally soluble proteins, or their fragments, as insoluble amyloid fibrils causes the usually fatal, acquired and hereditary systemic amyloidoses and is associated with the pathology of Alzheimer's disease, type 2 diabetes and the transmissible spongiform encephalopathies. Although each type of amyloidosis is characterised by a specific amyloid fibril protein, the deposits share...

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PMID: 10903851
DOI: 10.1006/jmbi.2000.3908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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