Article
p53 mutations as a marker of malignancy in bladder washing samples from patients with bladder cancer.
British journal of cancer - 1 Jan 2000
Phillips H A, Howard G C, Miller W R
Abstract excerpt
The diagnosis and follow-up of patients with bladder cancer rely on invasive procedures (cystoscopy with biopsy). Polymerase chain reaction (PCR)-based technologies may allow the sensitive detection of cancer-related genetic mutations in exfoliated tumour material, potentially allowing the development of less invasive techniques. This pilot study investigated the feasibility of detecting mutations in exons 5-8 of...
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