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Article

Comparison of P53 protein overexpression with P53 mutation in bladder cancer: clinical and biologic aspects.

Laboratory investigation; a journal of technical methods and pathology - 1 Dec 1995

Vet J A, Bringuier P P, Schaafsma H E, Witjes J A, Debruyne F M, Schalken J A

Abstract excerpt

BACKGROUND: Alterations of the tumor suppressor gene p53 are known to occur in bladder cancer. Although p53 overexpression is associated with mutation of the p53 gene, a substantial discrepancy between molecular genetic alteration in p53 and overexpression of the protein has been found. EXPERIMENTAL DESIGN: Tumor specimens of 39 bladder cancer patients were immunohistochemically analyzed for p53 overexpression,...

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PMID: 8558845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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