Article
p53 mutations have no additional prognostic value over stage in bladder cancer.
British journal of cancer - 1 Sept 1994
Vet J A, Bringuier P P, Poddighe P J, Karthaus H F, Debruyne F M, Schalken J A
Abstract excerpt
Evidence is accumulating that the tumour-suppressor gene p53 is involved in the development of bladder cancer. Therefore we studied p53 mutations in 47 bladder cancers obtained from 45 patients using polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) analysis. Eight out...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Base Sequence
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- DNA, Single-Stranded
- Gene Deletion
- Genes, p53
- Humans
- Middle Aged
