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Article

Diagnosis of bladder cancer by analysis of the allelic loss of the p53 gene in urine samples using blunt-end single-strand conformation polymorphism.

International journal of cancer - 22 Aug 1997

Sugano K, Tsutsumi M, Nakashima Y, Yamaguchi K, Ohkura H, Kakizoe T, Sekiya T

Abstract excerpt

The novel approach of blunt-end single-strand conformation polymorphism (SSCP) has been applied in the analysis of urine samples from bladder-cancer patients for detecting loss of heterozygosity (LOH) of 3 polymorphic markers in the p53 gene. Of the 28 urine samples examined by SSCP analysis of blunt-ended DNA fragments using a fluorescence-based automated sequencer, 16 were informative in more than 1 of the 3...

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PMID: 9291429
DOI: 10.1002/(sici)1097-0215(19970822)74:4<403::aid-ijc7>3.0.co;2-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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