Diagnosis of bladder cancer by analysis of the allelic loss of the p53 gene in urine samples using blunt-end single-strand conformation polymorphism.

doi:10.1002/(sici)1097-0215(19970822)74:4<403::aid-ijc7>3.0.co;2-z

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Article

Diagnosis of bladder cancer by analysis of the allelic loss of the p53 gene in urine samples using blunt-end single-strand conformation polymorphism.

International journal of cancer - 22 Aug 1997

Sugano K, Tsutsumi M, Nakashima Y, Yamaguchi K, Ohkura H, Kakizoe T, Sekiya T

Abstract excerpt

The novel approach of blunt-end single-strand conformation polymorphism (SSCP) has been applied in the analysis of urine samples from bladder-cancer patients for detecting loss of heterozygosity (LOH) of 3 polymorphic markers in the p53 gene. Of the 28 urine samples examined by SSCP analysis of b...

Topics

Alleles
Chromosome Deletion
DNA
DNA Primers
DNA, Neoplasm
Exons
Genes, p53
Genetic Carrier Screening
Humans
Introns
Neoplasm Staging
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Urinary Bladder Neoplasms

Source

Open in PubMed

Identifiers

PMID: 9291429
DOI: 10.1002/(sici)1097-0215(19970822)74:4<403::aid-ijc7>3.0.co;2-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9291429-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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