Article
Analyses of p53 gene mutations in primary human bladder cancer.
Oncology research - 1 Jan 1993
Miyamoto H, Kubota Y, Shuin T, Torigoe S, Hosaka M, Iwasaki Y, Danenberg K, Danenberg P V
Abstract excerpt
Mutations in the tumor suppressor gene p53 have been detected in many tumors. p53 gene mutations are also known to be involved in the progression of human bladder cancers. We investigated structural alterations in the entire coding region of the p53 gene in primary human bladder cancers, using polymerase chain reaction and single-strand conformational polymorphism analysis of RNA. Of 25 samples obtained from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.