Article
Comparative analysis of p53 mutations in bladder washings and histologic specimens.
American journal of clinical pathology - 1 Nov 1998
Vet J A, Hessels D, Marras S A, van de Kaa C A, van der Poel H G, Michalides R J, Debruyne F M, Schalken J A
Abstract excerpt
Mutations in the tumor suppressor gene p53, analyzed in bladder washings, have positive predictive value for the progression of superficial bladder cancer to invasive disease. Bladder washings reflect the general status of the urothelium, and because sampling of bladder washings can be performed...
Topics
- Genes, p53
- Humans
- Immunohistochemistry
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Sensitivity and Specificity
- Sequence Analysis
- Therapeutic Irrigation
- Tissue Embedding
- Tumor Suppressor Protein p53
- Urinary Bladder Neoplasms