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p53 mutations in human bladder cancer.

Environmental and molecular mutagenesis - 1 Jan 1994

Kusser W C, Miao X, Glickman B W, Friedland J M, Rothman N, Hemstreet G P, Mellot J, Swan D C, Schulte P A, Hayes R B

Abstract excerpt

Mutations in the tumor suppressor gene p53 play an important role in carcinogenesis and tumor progression. To assess the status of p53 from genomic DNA from bladder cancer samples a two stage polymerase chain reaction was employed. The technique provided material for subsequent detection of mutations by Single Strand Conformation Polymorphism (SSCP) analysis followed by DNA sequence analysis. SSCP analysis of...

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Identifiers

PMID: 7957118
DOI: 10.1002/em.2850240303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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