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Article

p53 mutations in human bladder cancer: genotypic versus phenotypic patterns.

International journal of cancer - 1 Feb 1994

Cordon-Cardo C, Dalbagni G, Saez G T, Oliva M R, Zhang Z F, Rosai J, Reuter V E, Pellicer A

Abstract excerpt

The objective of this study was to characterize the pattern of p53 mutations in bladder cancer. The sensitivity and specificity to detect these mutations using clinical material was assessed for the following assays: immunohistochemistry, restriction-fragment-length polymorphism, single-strand-conformation polymorphism, and sequencing. Discrepancies of reported results aimed at the identification of genetic...

Topics

Antibodies, Monoclonal
Chromosome Mapping
Chromosomes, Human, Pair 17
Genes, p53
Genotype
Humans
Immunohistochemistry
Mutation
Neoplasm Staging
Phenotype
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Sensitivity and Specificity

Tumor Suppressor Protein p53

Urinary Bladder Neoplasms

Source

Identifiers

PMID: 7906253
DOI: 10.1002/ijc.2910560309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7906253-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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