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Article

Nuclear pore complexes in the organization of silent telomeric chromatin.

Nature - 6 Jan 2000

Galy V, Olivo-Marin J C, Scherthan H, Doye V, Rascalou N, Nehrbass U

Abstract excerpt

The functional regulation of chromatin is closely related to its spatial organization within the nucleus. In yeast, perinuclear chromatin domains constitute areas of transcriptional repression. These 'silent' domains are defined by the presence of perinuclear telomere clusters. The only protein found to be involved in the peripheral localization of telomeres is Yku70/Yku80. This conserved heterodimer can bind...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10638763
DOI: 10.1038/47528

Genes

TPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nuclear pore complexes in the organization of silent telomeric chromatin.PMID 10638763Read ↗

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