Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast.

doi:10.1016/s0960-9822(02)01338-6

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Article

Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast.

Current biology : CB - 23 Dec 2002

Hediger Florence, Neumann Frank R, Van Houwe Griet, Dubrana Karine, Gasser Susan M

Abstract excerpt

BACKGROUND: The positioning of chromosomal domains within interphase nuclei is thought to facilitate transcriptional repression in yeast. Although this is particularly well characterized for telomeres, the molecular basis of their specific subnuclear organization is poorly understood. The use of live fluorescence imaging overcomes limitations of in situ staining on fixed cells and permits the analysis of...

Topics

Cell Nucleus
DNA Polymerase I
DNA-Binding Proteins
DNA-Directed DNA Polymerase
Fungal Proteins
Green Fluorescent Proteins
Histone Deacetylases
Image Processing, Computer-Assisted
In Situ Hybridization, Fluorescence
Interphase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Luminescent Proteins

Microscopy, Fluorescence

Mitosis

Mutation

S Phase

Saccharomyces cerevisiae Proteins

Signal Transduction

Silent Information Regulator Proteins, Saccharomyces cerevisiae

Source

Open in PubMed

Identifiers

PMID: 12498682
DOI: 10.1016/s0960-9822(02)01338-6

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