Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex.

doi:10.1128/MCB.01009-08

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Back to search

Article

Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex.

Molecular and cellular biology - 1 Feb 2009

Bystricky Kerstin, Van Attikum Haico, Montiel Maria-Dolores, Dion Vincent, Gehlen Lutz, Gasser Susan M

Abstract excerpt

We have examined the hypothesis that the highly selective recombination of an active mating type locus (MAT) with either HMLalpha or HMRa is facilitated by the spatial positioning of relevant sequences within the budding yeast (Saccharomyces cerevisiae) nucleus. However, both position relative to the nuclear envelope (NE) and the subnuclear mobility of fluorescently tagged MAT, HML, or HMR loci are largely...

Topics

Antigens, Nuclear
Cell Nucleus
Chromosomes, Fungal
DNA Breaks, Double-Stranded
DNA Repair
DNA-Binding Proteins
Gene Conversion
Genes, Mating Type, Fungal
Ku Autoantigen
Mutagenesis, Insertional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nuclear Envelope

Operator Regions, Genetic

Protein Binding

Rad52 DNA Repair and Recombination Protein

Recombination, Genetic

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 19047366
DOI: 10.1128/MCB.01009-08
PMCID: PMC2630671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex.PMID 19047366Read ↗

Yeast silent mating type loci form heterochromatic clusters through silencer protein-dependent long-range interactions.Semantic proximity Read ↗

Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast.Semantic proximity Read ↗

The association of yKu with subtelomeric core X sequences prevents recombination involving telomeric sequences.Semantic proximity Read ↗

Nuclear organization and transcriptional silencing in yeast.Semantic proximity Read ↗

Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins.Semantic proximity Read ↗

The Ku complex in silencing the cryptic mating-type loci of Saccharomyces cerevisiae.Semantic proximity Read ↗

Nuclear pore complexes in the organization of silent telomeric chromatin.Semantic proximity Read ↗

Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing.Semantic proximity Read ↗

Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres.Semantic proximity Read ↗

Silent chromatin determines target preference of the Saccharomyces retrotransposon Ty5.Semantic proximity Read ↗

Specific repression of the yeast silent mating locus HMR by an adjacent telomere.Semantic proximity Read ↗

Kluyveromyces lactis Sir2p regulates cation sensitivity and maintains a specialized chromatin structure at the cryptic alpha-locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.