Article
nup1 mutants exhibit pleiotropic defects in nuclear pore complex function.
The Journal of cell biology - 1 Oct 1994
Bogerd A M, Hoffman J A, Amberg D C, Fink G R, Davis L I
Abstract excerpt
The NUP1 gene of Saccharomyces cerevisiae encodes one member of a family of nuclear pore complex proteins (nucleoporins) conserved from yeast to vertebrates. We have used mutational analysis to investigate the function of Nup1p. Deletion of either the amino- or carboxy-terminal domain confers a l...
Topics
- Base Sequence
- Biological Transport
- Cell Nucleus
- DNA Mutational Analysis
- Fungal Proteins
- Genes, Fungal
- Membrane Proteins
- Microscopy, Electron
- Molecular Sequence Data
- Mutagenesis
- Nuclear Envelope
- Nuclear Pore Complex Proteins
- Nuclear Proteins
- Phenotype
- RNA, Fungal
- RNA, Messenger
- Saccharomyces cerevisiae
- Temperature