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Article

Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1.

Cell - 9 Jan 2004

Galy Vincent, Gadal Olivier, Fromont-Racine Micheline, Romano Alper, Jacquier Alain, Nehrbass Ulf

Abstract excerpt

The molecular mechanism underlying the retention of intron-containing mRNAs in the nucleus is not understood. Here, we show that retention of intron-containing mRNAs in yeast is mediated by perinuclearly located Mlp1. Deletion of MLP1 impairs retention while having no effect on mRNA splicing. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14718167
DOI: 10.1016/s0092-8674(03)01026-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14718167-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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