Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Telomere anchoring at the nuclear periphery requires the budding yeast Sad1-UNC-84 domain protein Mps3.

The Journal of cell biology - 3 Dec 2007

Bupp Jennifer M, Martin Adriana E, Stensrud Elizabeth S, Jaspersen Sue L

Abstract excerpt

Positioning of telomeres at the nuclear periphery can have dramatic effects on gene expression by establishment of heritable, transcriptionally repressive subdomains. However, little is known about the integral membrane proteins that mediate telomere tethering at the nuclear envelope. Here, we find a previously unrecognized function for the Saccharomyces cerevisiae Sad1-UNC-84 domain protein Mps3 in regulating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Nucleus
Share to Checkpoint Kinase 2
Share to Chromosomes, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Silencing

Share to S Phase

Share to Saccharomycetales

Share to Silent Information Regulator Proteins, Saccharomyces cerevisiae

Share to Telomere

Source

Open in PubMed Open full text

Identifiers

PMID: 18039933
DOI: 10.1083/jcb.200706040
PMCID: PMC2099192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Telomere anchoring at the nuclear periphery requires the budding yeast Sad1-UNC-84 domain protein Mps3.PMID 18039933Read ↗

The positioning of yeast telomeres depends on SIR3, SIR4, and the integrity of the nuclear membrane.Semantic proximity Read ↗

Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins.Semantic proximity Read ↗

The Sad1-UNC-84 homology domain in Mps3 interacts with Mps2 to connect the spindle pole body with the nuclear envelope.Semantic proximity Read ↗

Genetic analysis of Mps3 SUN domain mutants in Saccharomyces cerevisiae reveals an interaction with the SUN-like protein Slp1.Semantic proximity Read ↗

Genome-wide synthetic lethal screens identify an interaction between the nuclear envelope protein, Apq12p, and the kinetochore in Saccharomyces cerevisiae.Semantic proximity Read ↗

SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres.Semantic proximity Read ↗

Nuclear pore complexes in the organization of silent telomeric chromatin.Semantic proximity Read ↗

Mps3 SUN domain is important for chromosome motion and juxtaposition of homologous chromosomes during meiosis.Semantic proximity Read ↗

The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast.Semantic proximity Read ↗

mSin3-associated protein, mSds3, is essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells.Semantic proximity Read ↗

Nucleocytoplasmic trafficking of G2/M regulators in yeast.Semantic proximity Read ↗

Human Telomeres Are Tethered to the Nuclear Envelope during Postmitotic Nuclear AssemblySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.