Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of dietary intake and lifestyle factors on in vivo mutant frequency at the HPRT gene locus in healthy human subjects.

Mutation research - 17 Dec 1999

Barnett Y A, Warnock C A, Gillespie E S, Barnett C R, Livingstone M B

Abstract excerpt

This paper describes the results of a study designed to assess the effects of a variety of dietary and lifestyle factors on background levels of mutant frequency (MF) at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene locus in humans. Eighty-three healthy and free-living subjects (aged 20-80 yr; 61 males and 22 females; mean age of 63.07 +/- 14.71 yr) were recruited. Background levels of MF were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Aged, 80 and over
Share to Diet

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dietary Supplements

Share to Gene Frequency

Share to Hypoxanthine Phosphoribosyltransferase

Share to Life Style

Share to Multivariate Analysis

Source

Identifiers

PMID: 10635996
DOI: 10.1016/s0027-5107(99)00174-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of dietary intake and lifestyle factors on in vivo mutant frequency at the HPRT gene locus in healthy human subjects.PMID 10635996Read ↗

Effect of dietary components on hprt mutant frequencies in human T-lymphocytes.Semantic proximity Read ↗

Hprt mutant frequency and GSTM1 genotype in non-smoking healthy individuals.Semantic proximity Read ↗

Impact of age and environment on somatic mutation at the hprt gene of T lymphocytes in humans.Semantic proximity Read ↗

The influence of smoking and diet on the hypoxanthine phosphoribosyltransferase (hprt) mutant frequency in circulating T lymphocytes from a normal human population.Semantic proximity Read ↗

Factors affecting HPRT mutant frequency in T-lymphocytes of smokers and nonsmokers.Semantic proximity Read ↗

Mutant frequency at the hprt locus in human lymphocytes in a case-control study of lung cancer.Semantic proximity Read ↗

Calorie restriction modulates chemically induced in vivo somatic mutation frequency.Semantic proximity Read ↗

Factors influencing mutation at the hprt locus in T-lymphocytes: studies in normal women and women with benign and malignant breast masses.Semantic proximity Read ↗

Reduced proliferation rate of hypoxanthine-phosphoribosyl transferase mutant human T-lymphocytes in vitro.Semantic proximity Read ↗

Dietary fruit and vegetables protect against somatic mutation in vivo, but low or high intake of carotenoids does not.Semantic proximity Read ↗

Measurement of HPRT mutant frequencies in T-lymphocytes from healthy human populations.Semantic proximity Read ↗

Effect of caloric restriction on Hprt lymphocyte mutation in aging rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.