Mutant frequency at the hprt locus in human lymphocytes in a case-control study of lung cancer.

doi:10.1016/0027-5107(95)00161-8

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Article

Mutant frequency at the hprt locus in human lymphocytes in a case-control study of lung cancer.

Mutation research - 1 Nov 1995

Cheng T J, Christiani D C, Liber H L, Wain J C, Xu X, Wiencke J K, Kelsey K T

Abstract excerpt

A clonal assay to determine the mutant frequency (MF) at the hypoxanthine-guanine phosphoribosyl transferase (hprt) locus in human lymphocytes has been used by a number of investigators to study exposure to mutagens and carcinogens in a variety of populations. We have studied hprt MF in 106 subje...

Topics

Age Factors
Aged
Base Sequence
Case-Control Studies
Female
Gene Frequency
Humans
Hypoxanthine Phosphoribosyltransferase
Lung Neoplasms
Lymphocytes
Male
Middle Aged
Molecular Sequence Data
Mutation
Polymorphism, Genetic
Risk Factors
Smoking

Source

Open in PubMed

Identifiers

PMID: 7500985
DOI: 10.1016/0027-5107(95)00161-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7500985-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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