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Article

Mutant frequency at the hprt locus in human lymphocytes in a case-control study of lung cancer.

Mutation research - 1 Nov 1995

Cheng T J, Christiani D C, Liber H L, Wain J C, Xu X, Wiencke J K, Kelsey K T

Abstract excerpt

A clonal assay to determine the mutant frequency (MF) at the hypoxanthine-guanine phosphoribosyl transferase (hprt) locus in human lymphocytes has been used by a number of investigators to study exposure to mutagens and carcinogens in a variety of populations. We have studied hprt MF in 106 subjects (40 controls and 66 cases) enrolled in a case-control investigation of lung cancer. Epidemiological data collected...

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Identifiers

PMID: 7500985
DOI: 10.1016/0027-5107(95)00161-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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