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Article

Reduced proliferation rate of hypoxanthine-phosphoribosyl transferase mutant human T-lymphocytes in vitro.

Environmental and molecular mutagenesis - 1 Jan 1996

Podlutsky A, Bastlová T, Lambert B

Abstract excerpt

The clonal hprt mutation assay in human T-cell is based on the assumption that wild-type cells and hypoxanthine-phosphoribosyl transferase (hprt) mutant cells survive and proliferate at the same rate during the expression phase which is required for the expression of in vitro-induced mutants. We have tested this assumption in a study of mutant frequency (MF) and proliferation rate at different time points during...

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Identifiers

PMID: 8698041
DOI: 10.1002/(SICI)1098-2280(1996)28:1<13::AID-EM4>3.0.CO;2-F

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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