Article
Factors influencing mutation at the hprt locus in T-lymphocytes: studies in normal women and women with benign and malignant breast masses.
Environmental and molecular mutagenesis - 1 Jan 1992
Branda R F, O'Neill J P, Jacobson-Kram D, Albertini R J
Abstract excerpt
A prospective, longitudinal study was performed to test the hypothesis that environmental factors (e.g., diet or cigarette smoking) modulate genetic damage caused by treatment for breast cancer and render these women more susceptible to developing second malignancies. A total of 107 women (49 wit...
Topics
- Adult
- Aged
- Aging
- Breast Neoplasms
- Chromosome Aberrations
- Clone Cells
- Cloning, Molecular
- Female
- Folic Acid
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Longitudinal Studies
- Male
- Middle Aged
- Mutation
- Nutritional Physiological Phenomena
- Prospective Studies
- Reference Values