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Article

Effect of dietary components on hprt mutant frequencies in human T-lymphocytes.

Mutation research - 1 Mar 1995

Branda R F, Albertini R J

Abstract excerpt

The 6-thioguanine resistance (TGr) assay in human T-lymphocytes, which detects mutations at the hprt locus, identifies exposures to environmental mutagens. However, the ability of this assay to detect small increases in mutation rates is limited by the broad range of mutant frequencies (Mf) in healthy individuals. While subject age, lymphocyte cloning efficiency, and cigarette smoking history have been shown to...

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Identifiers

PMID: 7700275
DOI: 10.1016/0165-7992(95)90043-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of dietary components on hprt mutant frequencies in human T-lymphocytes.PMID 7700275Read ↗

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