Article
Effect of dietary components on hprt mutant frequencies in human T-lymphocytes.
Mutation research - 1 Mar 1995
Branda R F, Albertini R J
Abstract excerpt
The 6-thioguanine resistance (TGr) assay in human T-lymphocytes, which detects mutations at the hprt locus, identifies exposures to environmental mutagens. However, the ability of this assay to detect small increases in mutation rates is limited by the broad range of mutant frequencies (Mf) in he...
Topics
- Adult
- Age Factors
- Aged
- Breast Diseases
- Breast Neoplasms
- Diet
- Female
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Middle Aged
- Multivariate Analysis
- Mutagenicity Tests
- Mutation
- T-Lymphocytes