Article
Dietary fruit and vegetables protect against somatic mutation in vivo, but low or high intake of carotenoids does not.
Carcinogenesis - 1 Apr 2003
Nyberg Fredrik, Hou Sai-Mei, Pershagen Göran, Lambert Bo
Abstract excerpt
Epidemiological studies have demonstrated protective effects of vegetables and fruit on risk of cancer, but underlying mechanisms remain unclear. Intervention studies have in some cases contradicted previous epidemiological evidence, e.g. for beta-carotene supplementation and lung cancer, emphasizing the need for mechanistic data. We assessed in vivo mutagenic effects of several dietary items using the HPRT...
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