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Article

Blocking P-selectin protects from ischemia/reperfusion-induced acute renal failure.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 2000

Singbartl K, Green S A, Ley K

Abstract excerpt

Acute renal failure (ARF) in response to ischemia-reperfusion is thought to be associated with neutrophil infiltration. Neutrophil recruitment depends on adhesion molecules, including P-selectin. Our study sought to characterize the role of P-selectin in ischemia-reperfusion (I/R) -induced acute renal failure (ARF). In wild-type (wt) and P-selectin-deficient (P-/-) mice (both C57BL/6), ARF was induced by 32 min...

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Source

Identifiers

PMID: 10627279
DOI: 10.1096/fasebj.14.1.48

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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