Article
L-selectin and ICAM-1 mediate reperfusion injury and neutrophil adhesion in the warm ischemic mouse liver.
The American journal of physiology - 1 Dec 1998
Yadav S S, Howell D N, Gao W, Steeber D A, Harland R C, Clavien P A
Abstract excerpt
Leukocytes recruited during ischemia-reperfusion to the liver are important mediators of injury. However, the mechanisms of leukocyte adhesion and the role of adhesion receptors in hepatic vasculature remain elusive. L-selectin may critically contribute to injury, priming adhesion for later actio...
Topics
- Animals
- Cell Adhesion
- Hot Temperature
- Intercellular Adhesion Molecule-1
- Ischemia
- L-Selectin
- Liver
- Liver Circulation
- Mice
- Mice, Inbred C57BL
- Microcirculation
- Mutation
