Article
Phenotypic and functional characterization of kidney-infiltrating lymphocytes in renal ischemia reperfusion injury.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2006
Ascon Dolores B, Lopez-Briones Sergio, Liu Manchang, Ascon Miguel, Savransky Vladimir, Colvin Robert B, Soloski Mark J, Rabb Hamid
Abstract excerpt
T and B lymphocytes have been implicated in the pathogenesis of renal ischemia reperfusion injury (IRI). The trafficking of lymphocytes into kidneys during IRI has been postulated to underlie this effect, but has not been rigorously studied. We therefore characterized the lymphocyte populations infiltrating into mouse kidneys 3 and 24 h after renal IRI. Immunohistochemistry and flow cytometry staining of kidney...
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