Article
Renal ischemic-reperfusion injury in L-selectin-deficient mice.
The American journal of physiology - 1 Aug 1996
Rabb H, Ramirez G, Saba S R, Reynolds D, Xu J, Flavell R, Antonia S
Abstract excerpt
L-selectin on leukocyte surfaces mediates cell rolling on endothelium. L-selectin blockade with antibodies attenuated ischemic-reperfusion injury (IRI) in heart and skeletal muscle, but its role in renal IRI is unknown. We evaluated the role of L-selectin in renal IRI using L-selectin-deficient m...
Topics
- Animals
- Cell Membrane
- Cell Movement
- Homozygote
- Kidney
- L-Selectin
- Mice
- Mice, Mutant Strains
- Mutation
- Neutrophils
- Peritonitis
- Reperfusion Injury