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Article

Multiple mutations of the p53 gene in human mammary carcinoma.

Mutation research - 7 Dec 1999

Meng L, Lin L, Zhang H, Nassiri M, Morales A R, Nadji M

Abstract excerpt

Alteration of the p53 tumor suppressor gene is the most common genetic abnormality in human cancer. In breast cancer, depending on the stage of disease and method of detection, mutation rates of 25-60% have been observed. Multiple mutations of p53 gene in the same tumor however, are rarely reported. In this study we explored the frequency of multiple mutations of p53 gene in mammary carcinoma in a cohort of south...

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Identifiers

PMID: 10606817
DOI: 10.1016/s0921-8777(99)00053-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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