Article
Frequency and pattern of p53 gene mutation in a cohort of Spanish women with node-negative breast cancer.
International journal of oncology - 1 Sept 1999
Meng L, Lin L, Fresno M, Morales A R, Nadji M
Abstract excerpt
Ethnic, racial and regional differences in the frequency and pattern of p53 gene mutations have been well documented. Some of these differences have been shown to have an impact on the survival of patients with breast cancer. In this study we explored the frequency and pattern of p53 abnormality in a cohort of Spanish women with node-negative breast cancer using PCR, subcloning and DNA sequencing of archival...
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